MSAB
Modify Date: 2025-08-25 11:57:49
MSAB structure
|
Common Name | MSAB | ||
|---|---|---|---|---|
| CAS Number | 173436-66-3 | Molecular Weight | 305.349 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 456.5±55.0 °C at 760 mmHg | |
| Molecular Formula | C15H15NO4S | Melting Point | 152-154°C | |
| MSDS | N/A | Flash Point | 229.9±31.5 °C | |
Use of MSABMSAB is a selective inhibitor of Wnt/β-catenin signaling. MSAB shows potent anti-tumor effects selectively on Wnt-dependent cancer cells in vitro and in mouse cancer models. MSAB binds to β-catenin, promoting its degradation, and specifically downregulates Wnt/β-catenin target genes. |
| Name | MSAB |
|---|---|
| Synonym | More Synonyms |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 456.5±55.0 °C at 760 mmHg |
| Melting Point | 152-154°C |
| Molecular Formula | C15H15NO4S |
| Molecular Weight | 305.349 |
| Flash Point | 229.9±31.5 °C |
| Exact Mass | 305.072174 |
| LogP | 1.04 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.600 |
| InChIKey | CVKBYFCJQSPBOI-UHFFFAOYSA-N |
| SMILES | COC(=O)c1cccc(NS(=O)(=O)c2ccc(C)cc2)c1 |
| Storage condition | 2-8°C |
| Hazard Codes | Xi |
|---|
|
Name: Thermal stabilization of wildtype beta catenin ARD (148 to 662 residues) (unknown ori...
Source: ChEMBL
Target: Catenin beta-1
External Id: CHEMBL5105271
|
|
Name: Anticancer activity against human HCT-116 cells assessed as reduction in cell viabili...
Source: ChEMBL
Target: HCT-116
External Id: CHEMBL5226915
|
|
Name: Cell-based high throughput primary assay to identify activators of GPR151
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id: GPR151_PHUNTER_AG_LUMI_1536_1X%ACT
|
|
Name: AlphaScreen-based biochemical high throughput primary assay to identify activators of...
Source: The Scripps Research Institute Molecular Screening Center
Target: N/A
External Id: FBW7_ACT_ALPHA_1536_1X%ACT PRUN
|
|
Name: AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of...
Source: The Scripps Research Institute Molecular Screening Center
External Id: MITF_INH_Alpha_1536_1X%INH PRUN
|
Total 5, Current Page 1 of 1
1
| 3-(Toluene-4-sulfonylamino)-benzoic acid methyl ester |
| 3-[[(4-Methylphenyl)sulfonyl]amino]-benzoic acid methyl ester |
| Benzoic acid, 3-[[(4-methylphenyl)sulfonyl]amino]-, methyl ester |
| MFCD00994918 |