Name | Ertiprotafib | CAS# | 251303-04-5 | |
---|---|---|---|---|
Price | ¥Inquiry/1g | Purity | 98.9% | |
Stocking Period |
1 Day | Stock | In Stock |
Detail
Product Information
Ertiprotafib, also known as PTP-112, is a Protein Tyrosine Phosphatase 1B Inhibitor (PTP1B inhibitor). Ertiprotafib normalized the plasma glucose and insulin levels in diabetic animal models, and progressed to a phase II clinical trial. Ertiprotafib is potentially useful for the treatment of Non-Insulin Dependent Diabetes. Ertiprotafib improves glycemic control and lowers lipids via multiple mechanisms. Ertiprotafib is also a potent inhibitor of IkappaB kinase beta (IKK-beta), with an IC(50) of 400nM. |