PU-02

Published date: 2022-11-29 15:44:27
PU-02 Structure
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Name PU 02 CAS# 313984-77-9
Price ￥Inquiry/1g Purity 98.9%
Stocking
Period		 1 Day Stock In Stock
 Detail Product Information
PU-02 is a potent and selective 5-HT3 receptor antagonist. PU02 displays IC(50) values of ~1 μM at 5-HT(3)Rs and substantially lower activities at other Cys-loop receptors. In an elaborate mutagenesis study of the 5-HT(3)A receptor guided by a homology model, PU02 is demonstrated to act through a transmembrane intersubunit site situated in the upper three helical turns of TM2 and TM3 in the (+)-subunit and TM1 and TM2 in the (-)-subunit.
Supplier/Manufacture

ShangHai DC Chemicals Co.,Ltd verified supplier

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