GSK3368715

Published date: 2022-11-29 15:44:27
GSK3368715 Structure
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Name GSK3368715 CAS# 1629013-22-4
Price ￥Inquiry/1g Purity 98.9%
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Period		 1 Day Stock In Stock
 Detail Product Information
GSK3368715, aslo known as EPZ019997, is a potent, reversible type I PRMT inhibitor with anti-tumor effects in human cancer models. Inhibition of PRMT5, the predominant type II PRMT, produces synergistic cancer cell growth inhibition when combined with GSK3368715. Interestingly, deletion of the methylthioadenosine phosphorylase gene (MTAP) results in accumulation of the metabolite 2-methylthioadenosine, an endogenous inhibitor of PRMT5, and correlates with sensitivity to GSK3368715 in cell lines.
Supplier/Manufacture

ShangHai DC Chemicals Co.,Ltd verified supplier

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Address: Pudong new area Jin Yu road 100#
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Contact: Tony Lai
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Website: http://www.biomedgen.cn
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