Simvastatin acid ammonium

Published date: 2022-11-29 15:44:27

Simvastatin acid ammonium Structure
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Name Simvastatin ammonium salt CAS# 139893-43-9
Price ¥Inquiry/1g Purity 98.9%
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 Detail Product Information
Simvastatin ammonium is an active metabolite of simvastatin lactone mediated by CYP3A4/5 in the intestinal wall and liver (pKa=5.5). Simvastatin ammonium reduces indoxyl sulfate-mediated reactive oxygen species and modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene.

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