ML390

Published date: 2022-11-29 15:44:27
ML390 Structure
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Name ML390 CAS# 2029049-79-2
Price ￥Inquiry/1g Purity 98.9%
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Period		 1 Day Stock In Stock
 Detail Product Information
ML390 is a human DHODH Inhibitor That Induces Differentiation in Acute Myeloid Leukemia. ML390 bioactivity: ER-HOX-GFP (EC50 μM) = 1.8 ± 0.6; U937 (EC50 μM) = 8.8 ± 0.8; THP-1 (EC50 μM) = 6.5 ± 0.9; DHODH (IC50, μM) = 0.56 ± 0.1. ML390 may offer insight into the mechanism of overcoming differentiation arrest, and will translate into a starting point for a much-needed new and potent treatment for patients with acute myeloid leukemia. Inhibitors of dihydroorotate dehydrogenase (DHODH) showed activity to induce differentiation in multiple animal models of AML in vitro and in vivo. DHODH inhibitors demonstrated effective at prolonging survival in animal models of leukemia.
Supplier/Manufacture

ShangHai DC Chemicals Co.,Ltd verified supplier

Chemsrc Level: Verified
Product #: 14107
Tel: 58447131
Address: Pudong new area Jin Yu road 100#
Area: China
Contact: Tony Lai
Contact Phone #: 13564518121
Email: order@dcchemicals.com
Website: http://www.biomedgen.cn
Foreign Trade % of Sales: 20%
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Price: ￥2414/10 mM * 1 mL in DMSO
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2024-07-15 ML390
Price: Inquiry
2020-12-18 ML390
Price: $Inquiry
2021-02-06 ML390
Price: ￥1889.0

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