NI-42

Published date: 2022-11-29 15:44:27
NI-42 Structure
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Name NI 42 CAS# 1884640-99-6
Price ￥Inquiry/1g Purity 98.9%
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Period		 1 Day Stock In Stock
 Detail Product Information
NI-42 is a potent, selective and orally active BRPF1 bromodomain inhibitor with IC50 of 7.9 nM, with excellent selectivity over nonclass IV BRDs; weakly inhibits BRPF2 (BRD1), BRPF3, BRD9 and BRD4 (BD1) with IC50 of 48, 260, 310 and 4500 nM respectively, and no activity for ATAD2A/2B (IC50>100 uM); shows a modest (GI50=1-10 uM) and selective inhibition of proliferation of certain cancer lines, particularly those lines exhibiting monocytic lineage differentiation; a novel, structurally orthogonal chemical probe for the BRPFs suitable for cellular and in vivo studies.
Supplier/Manufacture

ShangHai DC Chemicals Co.,Ltd verified supplier

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2024-07-15 NI 42
Price: Inquiry
2020-01-06 NI-42
Price: $650.0
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Price: $Inquiry
2021-11-10 NI-42
Price: ￥Inquiry
2021-04-03 NI-42
Price: ￥389.0

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