AZD-4635
Modify Date: 2025-08-25 19:19:15
AZD-4635 structure
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Common Name | AZD-4635 | ||
|---|---|---|---|---|
| CAS Number | 1321514-06-0 | Molecular Weight | 315.73300 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C15H11ClFN5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of AZD-4635AZD4635 is a novel adenosine 2A receptor (A2AR) inhibitor with a Ki of 1.7 nM. |
| Name | 6-(2-chloro-6-methylpyridin-4-yl)-5-(4-fluorophenyl)-1,2,4-triazin-3-amine |
|---|---|
| Synonym | More Synonyms |
| Description | AZD4635 is a novel adenosine 2A receptor (A2AR) inhibitor with a Ki of 1.7 nM. |
|---|---|
| Related Catalog | |
| Target |
Ki: 1.7 nM (A2AR) |
| References |
| Molecular Formula | C15H11ClFN5 |
|---|---|
| Molecular Weight | 315.73300 |
| Exact Mass | 315.06900 |
| PSA | 77.58000 |
| LogP | 3.86490 |
| InChIKey | NCWQLHHDGDXIJN-UHFFFAOYSA-N |
| SMILES | Cc1cc(-c2nnc(N)nc2-c2ccc(F)cc2)cc(Cl)n1 |
| Storage condition | -20℃ |
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Name: Selectivity ratio of Ki for human A1AR expressed in HEK293 cells membrane to Ki for h...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5148526
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Name: Antagonist activity at A2AAR in human HEK293 cells assessed as inhibition of CGS21680...
Source: ChEMBL
Target: Adenosine receptor A2a
External Id: CHEMBL5148543
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Name: Antagonist activity at A2AAR in human T -cells assessed as increase in IL-2 productio...
Source: ChEMBL
Target: Adenosine receptor A2a
External Id: CHEMBL5148544
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Name: Antitumor activity against mouse 4T1 cells implanted in BALB/c mouse assessed as tumo...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL5148529
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Name: Displacement of [3H]ZM241385 from human A2AAR expressed in HEK293 cells membrane asse...
Source: ChEMBL
Target: Adenosine receptor A2a
External Id: CHEMBL5148523
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Name: Displacement of [3H]DPCPX from human A1AR expressed in HEK293 cells membrane assessed...
Source: ChEMBL
Target: Adenosine receptor A1
External Id: CHEMBL5148524
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| AZD-4635 |
| AZD4635 |
| 6-(2-Chloro-6-methyl-4-pyridinyl)-5-(4-fluorophenyl)-1,2,4-triazin-3-amine |