Tbaj-876
Published date: 2022-06-22 21:57:40
|
Name | TBAJ-876 | CAS# | 2332841-25-3 |
|---|---|---|---|---|
| Price | $Inquiry/100mg $Inquiry/250mg $Inquiry/1g | Purity | 98.0% | |
| Stocking Period |
3 Day | Stock | 3 | |
| Product Webpage: | https://www.dcchemicals.com/product_show-tbaj-876.html | |||
| Detail
Product Information
TBAJ-876 (TBAJ876) is a potent inhibitor of mycobacterial F-ATP synthase, inhibits ATP synthesis catalyzed by the mycobacterial F-ATP synthase with IC50 of 0.03 nM; TBAJ-876 shows depleting intrabacterial ATP (IC50=0.89 nM), and inhibiting growth of M. bovis BCG (MIC90=7.2 nM). TBAJ-876 binds to the ε subunit at BDQ's binding site. TBAJ-876 shows attractive antitubercular activity and efficacy in a murine tuberculosis model. TBAJ-876 shows attractive in vitro and in vivo activities against M. abscessus, similar to its BDQ parent. |
DC Chemicals Limited
Chemsrc Level: Verified
Product #: 34961
Tel: 58447131
Address: Jinyu Rd100, pudong
Area: China
Contact: Tony Cao
Contact Phone #: 13564518121
Email: sales@dcchemicals.com
Website: http://www.dcchemicals.com
Major Market:
Foreign Trade % of Sales:
Major partners: