SRX3177

Published date: 2022-06-22 21:57:40

SRX3177 Structure
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Name SRX3177 CAS# 2241237-51-2
Price $700.0/100mg $1200.0/250mg $2400.0/1g Purity 98.0%
Stocking
Period
3 Day Stock 3
Product Webpage: https://www.dcchemicals.com/product_show-srx3177.html
 Detail Product Information
SRX3177 is a potent, triple BRD4/PI3K/CDK4/6 inhibitor with nanomolar potency against PI3Kα (IC50=79 nM), BRD4 bromodomains (BD1 and BD2) (IC50=33 nM and 89 nM, respectively), and CDK4/6 (IC50=2.5/3.3 nM).SRX3177 is capable of targeting BRD4, PI3K and CDK4/6 simultaneously, induces apoptosis and cell cycle arrest and has in vitro efficacy in mantle cell lymphoma, hepatocellular carcinoma and neuroblastoma models.SRX3177 has antitumor efficacy in in vivo xenograft models and is less toxic than the combination of agents that inhibit individual targets.

Supplier/Manufacture

DC Chemicals Limited verified supplier

Chemsrc Level: Verified
Product #: 34963
Tel: 58447131
Address: Jinyu Rd100, pudong
Area: China
Contact: Tony Cao
Contact Phone #: 13564518121
Email: sales@dcchemicals.com
Website: http://www.dcchemicals.com
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