CCR2 Covalent-IN-14

Published date: 2022-06-22 21:57:40

Name	CCR2 Covalent-IN-14	CAS#	2714478-83-6
Price	$Inquiry/100mg $Inquiry/250mg $Inquiry/1g	Purity	98.0%
Stocking Period	3 Day	Stock	3
Product Webpage:	https://www.dcchemicals.com/product_show-ccr2covalent-in-14.html

Detail Product Information CCR2 covalent-IN-14 is a covalent, negative allosteric modulator (NAM) of CCR2, binds to intracellularly pocket of CCR2 with Ki of 4 nM.CCR2 covalent-IN-14 is more potent than non-covalent analogue and wash-resistant in functional assays (IC50=33 nM in GTPγS binding assay on U2OS-CCR2 cell membranes, IC50=4 nM in β-arrestin recruitment assays).CCR2 covalent-IN-14 displays little to no inhibitory potency on CCR1 and CCR5.The affinity of CCR2 covalent-IN-14 for both the C70S and C75S CCR2 mutants is significantly decreased compared to WT CCR2.

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: CCR2 Covalent-IN-14
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: CCR2 Covalent-IN-14
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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2024-07-17

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