SGC2085 Hydrochloride
Published date: 2021-02-19 10:23:51
|
Name | SGC2085 | CAS# | 1821908-49-9 |
|---|---|---|---|---|
| Price | ￥850.0/100mg ￥1500.0/250mg ￥3000.0/1g | Purity | 98.0% | |
| Stocking Period |
1 Day | Stock | 3 | |
| Product Webpage: | https://www.dcchemicals.com/product_show-sgc2085_hydrochloride.html | |||
| Detail
Product Information
SGC2085 is a Potent and Selective Coactivator Associated Arginine Methyltransferase 1 (CARM1) Inhibitor with an IC50 of 50 nM and more than undred-fold selectivity over other PRMTs. CARM1 is an important positive modulator of Wnt/β-catenin transcription and neoplastic transformation in colorectal cancer as well as a critical factor in estrogen-stimulated breast cancer growth, and its depletion results in decreased proliferation of myeloid leukemia cells in vivo. |
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