AMG-487
Published date: 2020-12-18 22:54:27
|
Name | AMG 487 | CAS# | 473719-41-4 |
|---|---|---|---|---|
| Price | $2500.0/1g $700.0/100mg $1200.0/250mg | Purity | 98.0% | |
| Stocking Period |
3 Day | Stock | 3 | |
| Product Webpage: | https://www.dcchemicals.com/product_show-AMG-487.html | |||
| Detail
Product Information
AMG 487 is a potent and selective antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3) with IC50 values of 8nM and 8.2nM for I-IP-10 and I-ITAC, respectively. AMG 487 prevents the chemokines I-IP-10 and I-ITAC from binding to CXCR3. In the cellular assays, AMG 487 inhibits CXCR3-mediated cell migration with IC50 values of 8nM, 15nM and 36nM for I-IP-10, I-ITAC and MIG, respectively. |
DC Chemicals Limited
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