BO-264
Published date: 2020-12-18 22:54:27
|
Name | BO-264 | CAS# | 2408648-20-2 |
|---|---|---|---|---|
| Price | $450.0/100mg $900.0/250mg $1750.0/1g | Purity | 98.0% | |
| Stocking Period |
3 Day | Stock | 3 | |
| Product Webpage: | https://www.dcchemicals.com/product_show-BO-264.html | |||
| Detail
Product Information
BO-264 is a highly potent and orally active transforming acidic coiled-coil 3 (TACC3) inhibitor with an IC50 of 188 nM and a Kd of 1.5 nM. BO-264 specifically blocks the function of FGFR3-TACC3 fusion protein. BO-264 induces spindle assembly checkpoint (SAC)-dependent mitotic arrest, DNA damage and apoptosis. BO-264 has broad-spectrum antitumor activity[1]. |
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