Name | PS315 | CAS# | 1221964-50-6 | |
---|---|---|---|---|
Price | $Inquiry/1g | Purity | 98.0% | |
Stocking Period |
3 Day | Stock | 3 | |
Product Webpage: | https://www.dcchemicals.com/product_show-PS315.html |
Detail
Product Information
PS315, a derivative of PS48, is an allosteric PKC inhibitor by binding to the PIF-pocket of aPKC and inducing a displacement of the active site residue Lys111. PS315 inhibits the full-length and catalytic domain constructs of PKCζ (IC50=10 μM) and PKCι (IC50=30 μM). PS315 has anti-cancer activity. |