SR-717 lithium
Published date: 2020-11-24 09:30:17
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Name | SR-717 | CAS# | 2375421-09-1 |
|---|---|---|---|---|
| Price | $600.0/100mg $1000.0/250mg $2000.0/1g | Purity | 98.0% | |
| Stocking Period |
Inquiry | Stock | 3 | |
| Product Webpage: | https://www.dcchemicals.com/product_show-SR-717.html | |||
| Detail
Product Information
SR-717 is a non-nucleotide, small-molecule STING agonist and functions as a direct cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) mimetic that induces the same "closed" conformation of STING.SR-717 functions as a direct cyclic guanosine monophosphate–adenosine monophosphate (cGAMP) mimetic that induces the same “closed” conformation of STING. SR-717 displayed antitumor activity; promoted the activation of CD8+ T, natural killer, and dendritic cells in relevant tissues; and facilitated antigen cross-priming. SR-717 also induced the expression of clinically relevant targets, including programmed cell death 1 ligand 1 (PD-L1), in a STING-dependent manner. |
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