Name | HKI272 maleate | CAS# | 915942-22-2 | |
---|---|---|---|---|
Price | $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg | Purity | 98.0% | |
Stocking Period |
1 Day | Stock | 3 | |
Product Webpage: | https://www.dcchemicals.com/product_show-HKI272_maleate.html |
Detail
Product Information
Neratinib, also known as HKI-272 or PB272, is an orally available, irreversible inhibitor of the HER-2 receptor tyrosine kinase with potential antineoplastic activity. Neratinib binds to the HER-2 receptor irreversibly, thereby reducing autophosphorylation in cells, apparently by targeting a cysteine residue in the ATP-binding pocket of the receptor. |