Name | NSC59984 | CAS# | 803647-40-7 | |
---|---|---|---|---|
Price | $350.0/100mg $700.0/250mg $1500.0/1g | Purity | 98.0% | |
Stocking Period |
3 Day | Stock | 3 | |
Product Webpage: | https://www.dcchemicals.com/product_show-NSC59984.html |
Detail
Product Information
NSC59984 induces mutant p53 protein degradation via MDM2 and the ubiquitin-proteasome pathway.The EC50 of NSC59984 in most cancer cells is significantly lower than those of normal cells, with EC50 of 8.38 μM for p53-null HCT116 cells. |