Letters in Organic Chemistry

Rapid and efficient synthesis of N-alkylbenzamides under microwave irradiation

JK Cermak, K Kolar, V Církva

Index: Cermak, Jan K.; Kolar, Karel; Cirkva, Vladimir Letters in Organic Chemistry, 2013 , vol. 10, # 2 p. 126 - 130

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Abstract

The microwave-assisted synthesis of N-alkylbenzamides from benzoic acid and primary aliphatic amines has been developed under solvent-free conditions. The different solid catalysts have been investigated. The suggested synthesis is environmentally friendly and excellent yields (97-99%) have been reached.