Tetrahedron

Synthesis and separation of the atropisomers of 2-(5-benzo [b] fluorenyl)-2′-hydroxy-1, 1′-binaphthyl and related compounds

H Yang, JL Petersen, KK Wang

Index: Yang, Hua; Petersen, Jeffrey L.; Wang, Kung K. Tetrahedron, 2006 , vol. 62, # 34 p. 8133 - 8141

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Citation Number: 8

Abstract

Several syn and anti atropisomers of 2-(5-benzo [b] fluorenyl)-2′-hydroxy-1, 1′-binaphthyl and related compounds were synthesized from 1, 1′-binaphthyl-2, 2′-diol (BINOL). It was possible to separate the syn and anti atropisomers by silica gel column chromatography. The syn atropisomers are potential hetero-bidentate ligands for complex formation with metals. By starting from enantiomerically pure (R)-(+)-BINOL and (S)-(−)-BINOL, four ...