Tetrahedron

Gel formation properties of a uracil-appended cholesterol gelator and cooperative effects of the complementary nucleobases

E Snip, K Koumoto, S Shinkai

Index: Snip, Erwin; Koumoto, Kazuya; Shinkai, Seiji Tetrahedron, 2002 , vol. 58, # 43 p. 8863 - 8873

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Citation Number: 46

Abstract

We designed and synthesized a uracil-appended cholesterol gelator (1) in order to control the gel stability and the gel morphology by addition of the complementary and non- complementary nucleobase derivatives. Compound 1 forms columnar stacks in cyclohexane due to the van der Waals interaction (cholesterol–cholesterol interaction) and the intergelator hydrogen bonding between uracil moieties. Addition of a 'monomeric' ...