Selective Iodine??Catalyzed Intermolecular Oxidative Amination of C (sp3) H Bonds with ortho??Carbonyl??Substituted Anilines to Give Quinazolines

…, Y Zhang, C Feng, Z Zha, Z Wang

Index: Yan, Yizhe; Zhang, Yonghui; Feng, Chengtao; Zha, Zhenggen; Wang, Zhiyong Angewandte Chemie - International Edition, 2012 , vol. 51, # 32 p. 8077 - 8081

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Citation Number: 84

Abstract

Transition-metal-catalyzed intermolecular or intramolecular direct oxidative aminations of C (sp3) ÀH bonds, including activated and unactivated C (sp3) ÀH bonds, have emerged as important methods for CÀN bond formations, because they are straightforward and have economic advantages over present procedures by employing prefunctionalized substrates (Scheme 1 a).[1–3] However, these aminations are restricted because of the toxicity of ...