New route to phenazine 5, 10-dioxides and related compounds

MJA El-Haj, BW Dominy, JD Johnston…

Index: El-Haj,M.J.A. et al. Journal of Organic Chemistry, 1972 , vol. 37, p. 589 - 593

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Citation Number: 19

Abstract

Certain phenazine 5, lO-dioxides are known to have antibacterial activity. Two of these, iodinin2 and myxin13s4 are microbial metabolites. Previously, compounds of this class were prepared in low yields by a multistep synthetic routes5 We now report a facile one-step synthesis of substituted phenazine 5, lO-dioxides and some related compounds. This versatile synthesis has afforded novel compounds hitherto inaccessible by classical ...