SYNTHESES IN THE CINCHONA SERIES. II. QUATERNARY SALTS.

WA Jacobs, M Heidelberger

Index: Heidelberger; Jacobs Journal of the American Chemical Society, 1919 , vol. 41, p. 1457

Full Text: HTML

Citation Number: 18

Abstract

In a recent communication a plan was outlid for the synthesis of aromatic arsenic compounds for biological study.'The present paper and that following it represent an attempt to apply a sknihxr method of treatment to the field of the cinchona alkaloids, whose possibilities as mterial for chemotherapeutic study in one direction have beea shown by the remarkable specifidty for the pneumococcus displayed by ethyl-hydrompreine. 2

 Related Synthetic Route
p-Amino-o-cresol Structure

2835-96-3

p-Amino-o-cresol

~%

Acetamide,N-(4-hydroxy-3-methylphenyl)- Structure

16375-90-9

Acetamide,N-(4-...

2-Ethoxyphenol Structure

94-71-3

2-Ethoxyphenol

~%

N-(3-ethoxy-4-hydroxyphenyl)acetamide Structure

135325-75-6

N-(3-ethoxy-4-h...

4-Amino-2-ethoxyphenol Structure

55483-70-0

4-Amino-2-ethox...

Ethanoic anhydride Structure

108-24-7

Ethanoic anhydride

~%

N-(3-ethoxy-4-hydroxyphenyl)acetamide Structure

135325-75-6

N-(3-ethoxy-4-h...

4-Amino-2-methoxyphenol Structure

52200-90-5

4-Amino-2-metho...

Chloroacetyl chloride Structure

79-04-9

Chloroacetyl ch...

~%

2-chloro-N-(4-hydroxy-3-methoxyphenyl)acetamide Structure

17640-79-8

2-chloro-N-(4-h...

m-Methoxyphenol Structure

150-19-6

m-Methoxyphenol

~%

2′,4′-Dimethoxyacetanilide Structure

23042-75-3

2′,4′-Dimethoxy...

4-[N-(4-hydroxy-2-methoxyphenyl)azo]benzenesulfonic acid Structure

106063-48-3

4-[N-(4-hydroxy...

~%

2′,4′-Dimethoxyacetanilide Structure

23042-75-3

2′,4′-Dimethoxy...

4-Amino-3-methoxyphenol Structure

61638-01-5

4-Amino-3-metho...

~%

2′,4′-Dimethoxyacetanilide Structure

23042-75-3

2′,4′-Dimethoxy...

N-(4-hydroxy-2-methoxyphenyl)acetamide Structure

5307-06-2

N-(4-hydroxy-2-...

Dimethyl sulfate Structure

77-78-1

Dimethyl sulfate

~%

2′,4′-Dimethoxyacetanilide Structure

23042-75-3

2′,4′-Dimethoxy...

Chloroacetyl chloride Structure

79-04-9

Chloroacetyl ch...

3-Ethoxyaniline Structure

621-33-0

3-Ethoxyaniline

~%

2-Chloro-N-(3-ethoxyphenyl)acetamide Structure

17641-12-2

2-Chloro-N-(3-e...

4-Amino-3-methoxyphenol Structure

61638-01-5

4-Amino-3-metho...

Ethanoic anhydride Structure

108-24-7

Ethanoic anhydride

~%

N-(4-hydroxy-2-methoxyphenyl)acetamide Structure

5307-06-2

N-(4-hydroxy-2-...

4-[N-(4-hydroxy-2-methoxyphenyl)azo]benzenesulfonic acid Structure

106063-48-3

4-[N-(4-hydroxy...

~%

N-(4-hydroxy-2-methoxyphenyl)acetamide Structure

5307-06-2

N-(4-hydroxy-2-...

3,4-diethoxyacetanilide Structure

84702-04-5

3,4-diethoxyace...

~%

3,4-Diethoxyaniline Structure

39052-12-5

3,4-Diethoxyaniline

2-Ethoxyphenol Structure

94-71-3

2-Ethoxyphenol

~%

3,4-Diethoxyaniline Structure

39052-12-5

3,4-Diethoxyaniline

4-Amino-2-ethoxyphenol Structure

55483-70-0

4-Amino-2-ethox...

~%

3,4-Diethoxyaniline Structure

39052-12-5

3,4-Diethoxyaniline

N-(3-ethoxy-4-hydroxyphenyl)acetamide Structure

135325-75-6

N-(3-ethoxy-4-h...

~%

3,4-Diethoxyaniline Structure

39052-12-5

3,4-Diethoxyaniline

3-Ethoxyphenol Structure

621-34-1

3-Ethoxyphenol

~%

N-(2,4-diethoxyphenyl)acetamide Structure

91204-39-6

N-(2,4-diethoxy...

Phenol,4-amino-3-ethoxy- Structure

139444-58-9

Phenol,4-amino-...

~%

N-(2,4-diethoxyphenyl)acetamide Structure

91204-39-6

N-(2,4-diethoxy...

Diethyl sulfate Structure

64-67-5

Diethyl sulfate

acetic acid-(2-ethoxy-4-hydroxy-anilide) Structure

861795-40-6

acetic acid-(2-...

~%

N-(2,4-diethoxyphenyl)acetamide Structure

91204-39-6

N-(2,4-diethoxy...

3-Ethoxyphenol Structure

621-34-1

3-Ethoxyphenol

~%

2,4-diethoxyaniline Structure

97-48-3

2,4-diethoxyaniline

Phenol,4-amino-3-ethoxy- Structure

139444-58-9

Phenol,4-amino-...

~%

2,4-diethoxyaniline Structure

97-48-3

2,4-diethoxyaniline

acetic acid-(2-ethoxy-4-hydroxy-anilide) Structure

861795-40-6

acetic acid-(2-...

~%

2,4-diethoxyaniline Structure

97-48-3

2,4-diethoxyaniline

N-(2,4-diethoxyphenyl)acetamide Structure

91204-39-6

N-(2,4-diethoxy...

~%

2,4-diethoxyaniline Structure

97-48-3

2,4-diethoxyaniline

acetic acid-(4-ethoxy-3-methoxy-anilide) Structure

86412-56-8

acetic acid-(4-...

~%

4-ethoxy-3-methoxy-benzenamin Structure

19782-77-5

4-ethoxy-3-meth...

3-Methoxy Acetaminophen Structure

3251-55-6

3-Methoxy Aceta...

~%

4-ethoxy-3-methoxy-benzenamin Structure

19782-77-5

4-ethoxy-3-meth...

4-Amino-2-methoxyphenol Structure

52200-90-5

4-Amino-2-metho...

~%

4-ethoxy-3-methoxy-benzenamin Structure

19782-77-5

4-ethoxy-3-meth...


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