Abstract Diphenyl phosphorazidate (DPPA) was used as the azide source in a one-pot synthesis of 2, 2-disubstituted 3-amino-2H-azirines 1 (Scheme 1). The reaction with lithium enolates of amides of type 2, bearing two substituents at C (2), proceeded smoothly in THF at 0; keteniminium azides C and azidoenamines D are likely intermediates. Under analogous reaction conditions, DPPA and amides of type 3 with only one substituent at C ( ...
