Chemistry: A European Journal 2012-04-27

Artificial electron carriers for photoenzymatic synthesis under visible light.

Sahng Ha Lee, Hye Jung Lee, Keehoon Won, Chan Beum Park

Index: Chemistry 18(18) , 5490-5, (2012)

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Abstract

NAD analogues can be employed as artificial electron carriers for photoenzymatic synthesis under visible light. Four different NAD analogues that have a 3-substituted pyridine ring have been investigated. 3-Acetylpyridine adenine dinucleotide and 3-pyridinealdehyde adenine dinucleotide were photochemically reduced much more efficiently than NAD, while their reduced products showed coenzyme activity comparable to natural NAD.Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.