Anticancer agents. IV. Antitumor activity of some 1, 4-and 1, 5-(bisthiosemicarbazones) and of related heterocycles

VC Barry, ML Conalty, JE McCormick…

Index: Barry,V.C. et al. Journal of Medicinal Chemistry, 1970 , vol. 13, p. 421 - 427

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Citation Number: 7

Abstract

I1 example of the well-known I'aal-Iinorr synthesis. Other pyrroles IIIb-d were prepared similarly. Reactionof 2 mol of 1-Ne-TSC with the diketorie gives the bisthiosemicarbazone IVb (cf. ref 5). 4-Mono-substituted TSC's in general react in this may to give IVa-g, but we have so far been unable to prepare his derivatives from TSC's with other types of substitution.