Journal of Combinatorial Chemistry 2006-01-01

Synthesis of platinum(II) chiral tetraamine coordination complexes.

Adel Nefzi, Cornelia E Hoesl, Clemencia Pinilla, George B Kauffman, Gerald M Maggiora, Elena Pasquale, Richard A Houghten

Index: J. Comb. Chem. 8(5) , 780-3, (2006)

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Abstract

The individual and combinatorial syntheses of individual as well as a mixture-based diversity of 195 112 platinum(II) coordination complexes of chiral tetraamines are described. The use of both solid-phase synthesis and solution phase follow-on approaches were found to best afford the title compounds.