Connection of metallamacrocycles via dynamic covalent chemistry: a versatile method for the synthesis of molecular cages

…, C Schouwey, T Riis-Johannessen…

Index: Granzhan, Anton; Schouwey, Clement; Riis-Johannessen, Thomas; Scopelliti, Rosario; Severin, Kay Journal of the American Chemical Society, 2011 , vol. 133, # 18 p. 7106 - 7115

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Citation Number: 93

Abstract

A modular approach for the synthesis of cage structures is described. Reactions of [(arene) RuCl2] 2 [arene= p-cymene, 1, 3, 5-C6H3Me3, 1, 3, 5-C6H3 (i-Pr) 3] with formyl-substituted 3-hydroxy-2-pyridone ligands provide trinuclear metallamacrocycles with pendant aldehyde groups. Subsequent condensation reactions with di-and triamines give molecular cages with 3, 6, or 12 Ru centers in a diastereoselective and chemoselective (self-sorting) fashion. ...