Farmakologiia i toksikologiia 1983-01-01

[Interaction of pipolfen and suprastin with human serum albumin depending on the pH of the medium and its calcium ion content].

K I Bender, A N Lutsevich

Index: Farmakol. Toksikol. 46(6) , 59-63, (1983)

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Abstract

Experiments made with the use of equilibrium dialysis and differential spectrophotometry have shown that pipolfen and difenhydramine interact actively with human serum albumin at pH 6.8-7.4. Calcium ions have been demonstrated to activate the interaction of pipolphen and diphenhydramine with albumin.