Synthesis, EPR, ENDOR and TRIPLE resonance investigations of anthracycline??related semiquinones

…, T Jülich, U Höfler, P Schuler, W Koch…

Index: Stegmann, Hartmut B.; Juelich, Thomas; Hoefler, Ulrike; Schuler, Paul; Koch, Wolfhard; et al. Magnetic Resonance in Chemistry, 1993 , vol. 31, # 5 p. 468 - 471

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Abstract

Abstract The synthesis of five substituted anthraquinones related to anthracyclines is described. One-electron reduction of these compounds yields the corresponding semiquinones, which were characterized by EPR, ENDOR and TRIPLE resonance spectroscopy. The data indicate a rapid conformational interconversion of the cyclohexene moiety (ring A in the anthracyclines). The low-temperature structures could be assigned to ...