Bioorganic & Medicinal Chemistry Letters 2008-10-15

Synthesis of nucleoside-based antiviral drugs in ionic liquids.

Vineet Kumar, Sanjay V Malhotra

Index: Bioorg. Med. Chem. Lett. 18(20) , 5640-2, (2008)

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Abstract

Nucleoside-based antiviral drugs have been synthesized using imidazolium-based ionic liquids as reaction medium. The ionic liquids were proved to be better solvents for all the nucleoside in terms of solubility and reaction medium as compared to conventional molecular solvents.