Abstract The synthesis of dihydrocytosines 4 from 3-aminopropionitriles 1 has been broadened and the dihydrocytosines themselves have now been successfully converted to cytosines 9. Unsubstituted 3-(H, alkyl or aryl) aminopropionitriles (1, X= H) convert with cyanate to 1-(H, alkyl or aryl)-1-(2-cyanoethyl) ureas (2, X= H), which in turn easily cyclize with anhydrous strong acid or base to 1-(H, alkyl or aryl)-5, 6-dihydrocytosines (4, X= H). ...
[Luk'yanov, O. A.; Gorelik, V. P.; Tartakovskii, V. A. Russian Chemical Bulletin, 1994 , vol. 43, # 1 p. 89 - 92 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1994 , # 1 p. 94 - 97]
