Molecules 2012-01-01

Diversity oriented syntheses of conventional heterocycles by smart multi component reactions (MCRs) of the last decade.

Heiner Eckert

Index: Molecules 17(1) , 1074-102, (2012)

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Abstract

A collection of smart multicomponent reactions (MCRs) with continuative post condensation cyclizations (PCCs) is presented to construct conventional three- to seven-membered heterocyclic compounds in diversity oriented syntheses (DOS). These will provide a high degree of applying economical and ecological advantages as well as of practicability. Water, ionic liquids, and solvent-less syntheses as well as use of various forms of energy as microwave and ultrasonic irradiation are examined and discussed.