Pest Management Science 2005-01-01

Antifungal properties of pristimerin and celastrol isolated from Celastrus hypoleucus.

Du-Qiang Luo, Hong Wang, Xuan Tian, Hong-Jun Shao, Ji-Kai Liu

Index: Pest Manag. Sci. 61(1) , 85-90, (2005)

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Abstract

Pristimerin and celastrol isolated from the roots of Celastrus hypoleucus (Oliv) Warb f argutior Loes exhibited inhibitory effects against diverse phytopathogenic fungi. Pristimerin and celastrol were found to inhibit the mycelial growth of Rhizoctonia solani Kuhn and Glomerella cingulata (Stonem) Spauld & Schrenk in vitro by 83.6 and 62.6%, respectively, at 10 microg ml(-1). Pristimerin showed good preventive effect (96.7% at 100 microg ml(-1)) and curative effect (66.5% at 100 microg ml(-1)) against wheat powdery mildew in vivo. For celastrol, the preventive and curative effects against wheat powdery mildew were 80.5 and 45.4%, respectively, at 100 microg ml(-1).