Bulletin of the Korean Chemical Society

Kinetic Study on Aminolysis of 4-Pyridyl X-Substituted Benzoates: Effect of Substituent X on Reactivity and Reaction Mechanism

JP Lee, AR Bae, IH Um

Index: Lee, Jong Pal; Bae, Ae Ri; Um, Ik-Hwan Bulletin of the Korean Chemical Society, 2011 , vol. 32, # 6 p. 1907 - 1911

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Abstract

Abstract A kinetic study is reported for nucleophilic substitution reactions of 4-pyridyl X- substituted benzoates 7a-e with a series of alicyclic secondary amines in H2O. The Br nsted- type plot for the reactions of 4-pyridyl benzoate 7c is linear with= 0.71. The corresponding reactions of 2-pyridyl benzoate 6, which is less reactive than 7c, resulted in also a linear Br nsted-type plot with= 0.77. The fact that the more reactive 7c results in a smaller value ...