Tetrahedron Letters

Cu (II)-catalyzed synthesis of quinoxalines from o-phenylenediamines and nitroolefins

Y Chen, K Li, M Zhao, Y Li, B Chen

Index: Chen, Yongxin; Li, Kangning; Zhao, Mingming; Li, Yuanjiao; Chen, Baohua Tetrahedron Letters, 2013 , vol. 54, # 13 p. 1627 - 1630

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Citation Number: 14

Abstract

An easy and efficient copper-catalyzed reaction for the synthesis of quinoxalines from o- phenylenediamines and nitroolefins is developed. This reaction could proceed well without additional base and be applied to various available substrates with a one-step synthetic procedure in moderate to good yields.

~90%

~60%

~40%

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