Tetrahedron letters

Synthesis of 4-arylaminoquinazolines via 2-amino-N-arylbenzamidines

W Szczepankiewicz, J Suwiński

Index: Szczepankiewicz, Wojciech; Suwinski, Jerzy Tetrahedron Letters, 1998 , vol. 39, # 13 p. 1785 - 1786

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Citation Number: 30

Abstract

A new synthesis of twelve 4-arylaminoquinazolines from 2-amino-N-arylbenzamidines and formic acid is described. The entering amidines were obtained in the reaction of anthranilonitrile with 50% molar excess of aromatic amines and anhydrous aluminium chloride.

~82%

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