Novel polymer-supported coupling/dehydrating reagents for use in organic synthesis

KE Fairfull-Smith, ID Jenkins…

Index: Fairfull-Smith, Kathryn E.; Jenkins, Ian D.; Longhlin, Wendy A. Organic and Biomolecular Chemistry, 2004 , vol. 2, # 14 p. 1979 - 1986

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Citation Number: 25

Abstract

Two novel dehydrating reagents 3 and 4, based on a phosphonium anhydride and an oxyphosphonium triflate respectively, were prepared by reaction of the corresponding polymer-supported phosphine oxides with triflic anhydride. Reagent 3, based on the novel phosphorus heterocycle 1, 1, 3, 3-tetraphenyl-2-oxa-1, 3-diphospholanium bis ( trifluoromethanesulfonate), was found to be a useful reagent for ester and amide formation ...