Chemoselective thioacetalization with odorless 2-(1, 3-dithian-2-ylidene)-3-oxobutanoic acid as a 1, 3-propanedithiol equivalent

H Yu, D Dong, Y Ouyang, Q Liu

Index: Yu, Haifeng; Dong, Dewen; Ouyang, Yan; Liu, Qun Canadian Journal of Chemistry, 2005 , vol. 83, # 10 p. 1741 - 1745

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Citation Number: 13

Abstract

Odorless 2-(1, 3-dithian-2-ylidene)-3-oxobutanoic acid (1c) was prepared and investigated in the thioacetalization of carbonyl compounds as a 1, 3-propanedithiol equivalent. The results showed that the thioacetalization of various carbonyl compounds 2 with 1c proceeded smoothly and afforded the corresponding dithioacetals 3 in high yields (up to 99%) in the presence of acetyl chloride at room or reflux temperatures. Moreover, the ...

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