... Please enable JavaScript to use all the features on this page. European Journal of Medicinal Chemistry. ... Controls (20), 6.5, 10.8, 1.1 cm 3, 1.9 cm 3. 40 mg/k (15), 4.2, 5.8, 0.6 cm 3, 0.7 cm 3. a ... Reactions were monitored by TLC using pre-coated silica gel aluminum plates containing a fluorescence indicator. Chemical shifts of 1 H NMR spectra were given in parts per million with respect to TMS, and the coupling constant J was measured in Hz. ...