Organic Letters 2000-04-20

Synthesis of functionalized oxazolines and oxazoles with DAST and Deoxo-Fluor.

A J Phillips, Y Uto, P Wipf, M J Reno, D R Williams

Index: Org. Lett. 2(8) , 1165-8, (2000)

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Abstract

[formula: see text] A mild and highly efficient cyclization of beta-hydroxy amides to oxazolines is described using DAST and Deoxo-Fluor reagents. A one-pot protocol for the synthesis of oxazoles from beta-hydroxy amides is also presented.