Abstract Tetrahydropyranyl (THP) derivatives of alcohols are converted in one-pot and in stereoselective manner into the corresponding 1-O-alkyl-2, 3, 5-tri-O-benzoyl-β-D- ribofuranosides on treatment with 1-O-acetyl-2, 3, 5-tri-O-benzoyl-β-D-ribofuranose and trimethylsilyl triflate (TMSOTf). The same protocol was also applyed on 1-O-acetyl-2, 3, 4, 6- tetra-O-benzyl-glucopyranoside (α/β 9: 1) to give, by reaction with 1-O-methyl-2, 3, 4-tri-O- ...
