Nucleic Acids Symposium Series 1984-01-01

Studies on oxidative modifications of nucleic acid pyrimidine bases.

T Harayama, R Yanada, K Kotoji, F Yoneda, T Taga, K Osaki, T Nagamatsu

Index: Nucleic Acids Symp. Ser. (15) , 1-4, (1984)

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Abstract

Oxidation of diacetylthymidine (4), triacetyluridine (5), and 5-fluoro-1,3-dimethyluracil (3) with m-chloroperbenzoic acid and cross-linkage of the bromohydrin (6) with the benzylamine and glycine ethyl ester are described. A Plausible mechanism for formation of oxidation products is also presented.