One??Pot Approach to Installing Eight??Membered Rings onto Indoles

C Zhu, X Zhang, X Lian, S Ma

Index: Zhu, Can; Zhang, Xue; Lian, Xiongdong; Ma, Shengming Angewandte Chemie - International Edition, 2012 , vol. 51, # 31 p. 7817 - 7820

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Citation Number: 22

Abstract

Eight-membered rings combined with an aromatic skeleton, a class of fused eight- membered compounds, have attracted considerable attention.[1, 2] Such units have been found in various natural products as well as in pharmacologically active substances:[3, 4] Iprindole (1),[5] the first second-generation antidepressant (TCA), and jolynamine (2),[6] which was isolated from a dark brown alga belonging to the family Scytosiphonaceae, ...