Chemistry Letters

Direct optical resolution of carboxylic acids by chiral HPLC on tris (3, 5-dimethylphenylcarbamate) s of cellulose and amylose

Y Okamoto, R Aburatani, Y Kaida, K Hatada

Index: Okamoto, Yoshio; Aburatani, Ryo; Kaida, Yuriko; Hatada, Koichi Chemistry Letters, 1988 , p. 1125 - 1128

Full Text: HTML

Citation Number: 89

Abstract

A variety of racemic carboxylic acids have been for the first time directly resolved by normal- phase, high-performance liquid chromatography using a hexane-2-propanol eluting system containing a small amount (≈ 1%) of a strong carboxylic acid, like formic acid, trichloroacetic acid, and trifluoroacetic acid.