Urology 2011-01-01

Effect of the Phytotherapeutic Agent Eviprostat on Inflammatory Changes and Cytokine Production in a Rat Model of Nonbacterial Prostatitis

Hiroyuki Tsunemori, Mikio Sugimoto, Zhang Xia, Rikiya Taoka, Michiko Oka, Yoshiyuki Kakehi

Index: Urology 77(6) , 1507.e15-20, (2011)

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Abstract

Objectives To examine the effect of the phytotherapeutic agent Eviprostat on the stromal-to-epithelial (S/E) ratio, level of macrophage infiltration, expression of the macrophage inhibitory cytokine-1 ( Mic1) gene, and tumor necrosis factor-alpha (TNF-α) and interleukin-8 (IL-8) concentrations in prostate tissues in a rat model of nonbacterial prostatitis (NBP).