Organic Letters 2004-06-10

SimplePHOX, a readily available chiral ligand system for iridium-catalyzed asymmetric hydrogenation.

Sebastian P Smidt, Frederik Menges, Andreas Pfaltz

Index: Org. Lett. 6 , 2023-2026, (2004)

Full Text: HTML

Abstract

[reaction: see text] New Ir-SimplePHOX complexes Ir-6-Ir-9 catalyze the quantitative, highly enantioselective hydrogenation of a range of unfunctionalized and functionalized olefins. Synthesis, catalytic results, and X-ray crystal structures are presented here.