Analogs of 8-[[6-(diethylamino) hexyl] amino]-6-methoxy-4-methylquinoline as candidate antileishmanial agents

MP LaMontagne, D Dagli, MS Khan…

Index: LaMontagne, Maurice P.; Dagli, Dinesh; Khan, M. Sami; Blumbergs, Peter Journal of Medicinal Chemistry, 1980 , vol. 23, # 9 p. 981 - 985

Full Text: HTML

Citation Number: 11

Abstract

Biological Activity. The compounds were tested for antileishmanial activity against L. donovani in hamster^.^ The data are shown in Table I. A comparison of the antileishmanial activity of each test compound with that of the reference compound, meglumine antimoniate, was made and a G index (relative activity of the test compound to that of the reference compound) for each test compound was calculated by the following formula: SD, for ...