Synthesis of 10??amino??9??aryl??2, 3, 4, 5, 6, 7, 9, 10??octahydroacridine??1, 8??dione derivatives

GF Han, B Cui, LZ Chen, XL Hu

Index: Han, Guang-Fan; Cui, Bin; Chen, Li-Zhuang; Hu, Xiao-Lei Journal of Heterocyclic Chemistry, 2012 , vol. 49, # 1 p. 195 - 199

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Citation Number: 2

Abstract

Abstract A series of novel 10-amino-9-aryl-2, 3, 4, 5, 6, 7, 9, 10-octahydroacridine-1, 8-dione derivatives 4 were synthesized by hydrazine or phenylhydrazine and 9-aryl-1, 8-dioxo-2, 3, 4, 5, 6, 7, 9-heptahydroxanthene derivatives 3, which were prepared by 5-substituted-1, 3- cyclohexanedione 1 and aromatic aldehydes 2 in the presence of concentrated H 2 SO 4 as a catalyst in water. The structures of all compounds were characterized by IR, MS, 1 H- ...